Use of Organoids in Cancer Research (C4 News)

Hayley Francies from the Sanger explains to Channel 4 reporter Tom Clark how the organoids are a more realistic tool for cancer research than typical monolayer cells

Hayley Francies from the Sanger explains to Channel 4 reporter Tom Clark how the organoids are a more realistic tool for cancer research than typical monolayer cells

Broadcaster: Channel 4

Year: 2015

Genre: News

URL: http://bobnational.net/record/294015

This 3.2 minute clip from Channel 4 looks at the use of organoids. Scientists at the Wellcome Trust Sanger Institute have, for the first time, grown tumours from 20 different colon cancer patients using matrigel to encourage the cells to form 3D “miniorgans” rather than growing in a monolayer as is more typical for cultured cells. Each organoid is different, reflecting the genetic errors in the donor, effectively a copy of the individual patients cancer grown in the lab. As a result a collection of tissues suitable for screening of existing and new drugs have been generated which may help both to select the most suitable drug for a given patient but also to improve our understanding of the cancers.

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One thought on “Use of Organoids in Cancer Research (C4 News)

  1. Pingback: The Donation Dilemma | Biology on the Box

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